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Physicians Dr. Carroll came to Mount Sinai School of Medicine in 2001 to serve as the Chief of the MSNYU Health Pediatric Oncology Program at the New York University and Mount Sinai Schools of Medicine. He is also a Professor in the Mount Sinai Department of Pediatrics. Dr. Carroll also leads a research team that is directed toward discovering new approaches to the treatment of childhood cancer, especially leukemias and the common solid tumor neuroblastoma. His work capitalizes on recent advances in decoding the human genome in order to develop a molecular fingerprint of childhood cancer. Results show that the expression of certain genes can predict how a patient will respond to treatment and the long-term goal is to use this information to tailor therapy individually. Another aspect of his research therapy seeks to understand how leukemia cells die in response to conventional therapy and how they evade the effects of chemotherapy. He has identified two "death pathways" in childhood acute lymphoblastoic leukemia and his research is now focused on identifying agents that promote death in cancer cells without harming normal cells. A third project is directed toward understanding how the N-Myc protein leads to such a poor outcome in neuroblastoma. Children whose tumors carry additional copies of this gene have a poor prognosis. Dr. Carroll is dissecting the molecular mechanisms that regulate expression of this gene and, in turn, how the N-Myc protein regulates the expression of other genes that are directly responsible for the malignant behavior of cancer cells. In addition to laboratory work, Dr. Carroll is directing clinical trials and has a specific focus on relapsed Acute Lymphoblastic Leukemia (ALL). He was recently appointed as Head of the Children's Oncology Group Acute Lymphoblastic Leukemia Disease Committee and is responsible for developing and directing clinical research in North America for children with ALL.Dr. Carroll received his medical degree from the University of California at Irvine. He completed his internship and residency in Pediatrics at Children's Hospital Medical Center in Cincinnati. He completed his fellowship in Pediatric Hematology Oncology at Stanford University and the Children's Hospital at Stanford. Dr. Carroll has been a member of the faculty at Washington University School of Medicine in St. Louis and the University of Utah School of Medicine in Salt Lake City. Publications for William L. Carroll, MD Dr. Blei is Director of the Long-term Follow-up Program for Survivors of Childhood Cancer and is Medical Director of the Vascular Anomalies Program. Dr. Blei is also an Associate Professor in the NYU Departments of Pediatrics and Plastic Surgery. Her specialty is Pediatric Hematology/Oncology Her clinical and research interests include Pediatric Hematology and the management and causes of vascular abnormalities. She received her medical degree from Sackler School of Medicine and completed her residency in Pediatrics at Bellevue/NYU Medical Center. She completed a clinical fellowship in Pediatric Hematology/Oncology at Babies Hospital and a research fellowship at Bellevue/NYU Medical Center. She holds board certifications in Pediatrics and Pediatric Hematology/Oncology. Dr. Brownstein is an Instructor in the Mount Sinai Department of Pediatrics. Her clinical interests include hematologic malignancy and long-term follow-up of childhood cancer survivors. Her specialties are Pediatrics and Pediatric Hematology/ Oncology. She received her medical degree from Tufts University School of Medicine Pediatrics residency training at Columbia Presbyterian/Babies Hospital. She completed a Pediatric Hematology and Oncology Fellowship at Memorial Sloan Kettering Cancer Center and New York Presbyterian Hospital/Cornell Medical Center. Research interests include understanding apoptotic pathways in childhood leukemia under the mentorship of William Carroll, MD, as well as late effects of chemotherapy and BMT on survivors of childhood cancer. Dr. Finlay is a Professor of Pediatrics at New York University School of Medicine and has been the Director of the Pediatric Neuro-oncology Program at New York University since moving to the institution from Memorial Sloan-Kettering Cancer Center in October 1997. Dr. Finlay is a pediatric oncologist whose professional career over the past 20 years has focused on the development of innovative therapies for childhood brain tumors. He has directed numerous clinical trials for the Children’s Oncology Group and was Chair of the Brain Tumor Strategy Group between 1985 to 1992. He continues to design new approaches to the treatment of refractory brain tumors and is a pioneer in the use of high dose chemotherapy with stem cell rescue for these conditions Dr. Finlay was the recipient of the Achievement Award in Clinical Pediatric Neuro-oncology of the Society of Neuro-oncology in 2001. Dr. Finlay serves as either Medical Director or Medical Advisory Board Member of several philanthropic foundations dedicated to childhood brain tumors. He received his MD from the University of Birmingham School of Medicine in England. He completed his residency in Pediatrics at Birmingham Children's Hospital, England and in Pediatrics and Pediatric Oncology at The Christi Hospital, Manchester, England. He completed clinical fellowships in Pediatric Immunology and Pediatric Hematology/Oncology at the University of Wisconsin in Madison. He is board certified in Pediatric Hematology/Oncology. Dr. Gardner is the Director of the Pediatric Stem Cell Transplant Program at Mount Sinai and NYU. She is an Assistant Professor in the NYU Department of Pediatrics. Her specialties are Pediatrics and Pediatric Hematology/Oncology. Dr. Gardner's clinical and research interests include stem cell transplantation, brain tumors, Hodgkin's disease, and palliative care. She is a recognized leader in the field of high dose chemotherapy followed by stem cell rescue for refractory tumors. She obtained her medical degree from Hahnemann University and completed her Pediatric internship and residency at St. Christopher's Hospital for Children. Dr. Gardner completed a clinical fellowship in Pediatric Hematology/Oncology at Memorial Sloan Kettering Cancer Center and The New York Hospital/Cornell Medical Center, where she served as Chief Fellow. Dr. Gardner was previously a member of the faculty at Memorial Sloan Kettering Cancer Center. She holds board certifications in Pediatrics and Pediatric Hematology/Oncology. Dr. Hurlet is an Associate Professor in the Department of Pediatric and Acting Director of the Hemophilia Center at Mount Sinai. Her clinical interest is in Hematology. Her basic and clinical research have been focused on neonatal hemostasis, thrombosis, stroke prevention in Sickle Cell disease. She directs the Hemophilia and the Sickle Cell Disease programs on the Mount Sinai campus. Those comprehensive programs focus on a multidisciplinary approach to the patient, close collaboration with the primary physician and the possibility of participating in cutting-edge medical research. Dr.
Hurlet received her medical degree from Liege University in Belgium.
She completed her internship and residency in Pediatrics at Liege
University and at the University of Medicine and Dentistry of New
Jersey. She completed her fellowship in Pediatric Hematology Oncology
at New York University School of Medicine. Dr. Hurlet has established
hemophilia and sickle cell programs at Columbia University and the
University of Medicine and Dentistry of New Jersey. Publications for Anne M. Hurlet, M.D. Dr. Levy is an Assistant Professor in the NYU Department of Pediatrics. His main clinical interests are pediatric cancers with a special interest in solid tumors. His laboratory research has focused on understanding why certain tumor cells are resistant to chemotherapy. Dr. Levy received his medical degree from the NYU School of Medicine. He completed his residency and was a Chief Resident in Pediatrics at the Mount Sinai Medical Center. He completed his fellowship in Pediatric Hematology and Oncology at Memorial Sloan-Kettering Cancer Center and The New York Hospital/Cornell Medical Center. Dr. Manwani is an Assistant Professor in the Mount Sinai Department of Pediatrics. Her research focuses on laying down the groundwork for the future use of gene therapy to treat sickle cell disease and beta thalassemia, a type of inherited anemia. In these endeavors Dr. Manwani works under the mentorship of Dr. James J. Bieker in the Department of Molecular, Cell and Developmental Biology. Dr. Manwani's clinical interests include Pediatric Hematology with a special focus on genetic disorders of the hemoglobin. Her specialities are Pediatrics and Pediatric Hematology/ Oncology. Dr. Manwani received her medical degree from B.J. Medical College, Pune University, in Pune, India. She completed her medical residency in Pediatrics at North Shore University Hospital in New York. She completed her fellowship in Pediatric Hematology Oncology at Mount Sinai Medical Center. Dr. Mitchell is an Instructor in the Mount Sinai Department of Pediatrics. His research focuses on investigating underlying cellular causes of the rare bleeding disorder, Glanzmann thrombasthenia. He works in the laboratory of Dr. Deborah French and in the laboratory group of Dr. Barry Coller. Dr.
Mitchell received his medical degree from Tufts University School
of Medicine. He completed his internship and residency in Pediatrics
at Boston City Hospital and Boston Medical Center. He came to the
Mount Sinai School of Medicine to complete his fellowship in Pediatric
Hematology Oncology.
Publications for W. Beau Mitchell, M.D., Instructor Dr. Raetz is an Assistant Professor in the Mount Sinai Department of Pediatrics. Her clinical research interests include Pediatric Oncology with a focus on childhood leukemia and non-Hodgkin's lymphoma. She is working within the Children's Oncology Group on treatment approaches for children with relapsed hematologic malignancies, and serves as the Principal Investigator for Children's Oncology Group clinical trials at Mount Sinai. Dr. Raetz is working in collaboration with Dr. William Carroll on studies of the genetic profiles of childhood leukemia. Dr. Raetz received her medical degree from the University of Wisonsin-Madison, where she also completed her Pediatric internship and residency. She completed fellowship training in Pediatric Hematology-Oncology at the University of Utah. She holds Board certifications in Pediatrics and Pediatric Hematology-Oncology. Dr. Rausen was the founding Director of the Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders at NYU Medical Center. He is also a Professor in the NYU Department of Pediatrics. Dr. Rausen received his MD from SUNY Brooklyn. He completed his internship at Bellevue Hospital Center and his residency at Bellevue Hospital Center and the Mount Sinai Medical Center. He held a clinical fellowship at Children's Hospital Medical Center (Pediatric Hematology) and is board certified Pediatrics and Hematology. An active member of the Children’s Oncology Group, Dr. Rausen serves as the Principal Investigator for the NYU Medical Center. Dr. Wistinghausen is a Clinical Instructor in the NYU Department of Pediatrics. Her laboratory and clinical research is focusing on medulloblastoma, the most common malignant brain tumor in childhood, and retinoids, a group of drugs that can induce differentiation and/or death in some tumor cells. She is investigating whether retinoids can improve the prognosis of children with medulloblastoma as well as the molecular pathways in medulloblastoma, which are affected by retinoid treatment. These research interests are supported by the outstanding mentorship of Dr. Herbert Samuels, Chairman of Pharmacology at NYU School of Medicine and Dr. Jonathan Finlay, Director of Neuro-Oncology at NYU Medical Center. Dr. Wistinghausen's clinical interests include pediatric cancers with special focus on medulloblastomas. Her specialities are Pediatrics and Pediatric Hematology/Oncology. Dr.
Wistinghausen received her medical degree from the Christian-Albrecht-University
in Kiel, Germany. She spent two years of research in the laboratory
of Dr. Margaret Karpatkin studying the molecular causes of afibrinogenemia
and factor XI deficiency. She completed her residency in Pediatrics
and her fellowship in Pediatric Hematology-Oncology at NYU Medical
Center and Bellevue Hospital Medical Center. Psychologist Dr. Cruz Arrieta is a Clinical Instructor in the Department of Psychiatry of the NYU Medical Center/Bellevue Clinical Psychology Doctoral Internship Program and Senior Psychologist, NYU Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders. Her research and clinical interests include the psychosocial effects of chronic illness and post-traumatic stress; parenting stress; culture, migration, and ethnicity; the psychological development of women; and psychology and the arts. Dr. Cruz Arrieta obtained her Ph.D. in Clinical Psychology from the City University of New York Graduate School and her Licensure from the New York State Department of Education. She completed an internship in Clinical Psychology at Bellevue Hospital Center and fellowships in Psychotherapy at New York University Medical Center and The Oasis Guidance Center (HIV/AIDS) in Bronx, NY. |
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