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Publications

William L. Carroll, MD, Director, MSNYU Health Pediatric Oncology Program
1.
Sivak LE, Dillon PA, Smith R, Brodeur G and Carroll WL: N-myc gene autoregulation is lost in amplified but not single copy neuroblastoma cell lines Oncogene 15: 1937-1946, 1997.

2. Bruggers CS, Fults D, Perkins SL, Coffin CM, and Carroll WL. Expression of apoptotic genes in brain tumors. J Pediatr Hematol Oncol 21: 19-25, 1999.

3. Sivak LE, Pont-Kingdon G, Le K, Mayr G, Tai K-F, Stevens BT, and Carroll WL. A novel intron element operates post-transcriptionally to regulate human N-myc expression. Mol Cell Biol. 19: 155-163, 1999.

4. Fang-Tai, K, Rogers, S., Pont-Kingdon, G. and Carroll, WL. Definition of the human N-myc promoter region during development. Ped Research 46: 255-262, 1999

5. Liu T, Raetz E, Moos PJ, Perkins SL, Bruggers CS, Smith F, Carroll WL. Diversity of the Apoptotic Response to Chemotherapy in Childhood Leukemia. Leukemia 16: 223-232, 2002.

6. Raetz EA, Moos PJ, Szabo A and Carroll WL. Gene Expression Profiling: Methods and Clinical Applications. Hematology and Oncology Clinics of North America 15:911-930, 2002.

7. Szabo A, Boucher K, Carroll WL, Klebanov LB, Tsodikov AD and Yakovlev AY. Variable selection and pattern recognition with gene expression data generated by microarray technology. Math Biosci 176: 71-98, 2002.

8. Slayton W and Carroll WL. Hematological Diseases of the Newborn Infant. In Rudolph’s Textbook of Pediatrics. CD Rudolph, AM Rudolph, M Hostetter, G Lister and N Siegel eds. McGraw-Hill Medical Publishing Co. (in press).

9. Moos PJ, Raetz EA, Carlson MA, Smith FE, Hunger SP, Wei Q and Carroll WL. Identification of gene expression profiles that segregate patients with childhood leukemia. Clin Cancer Res 10 3118-3130 2002.

10. Raetz EA, Perkins SL, Carlson MA, Schooler KP, Carroll WL, Virshup DM. The NPM-ALK Fusion Protein Induces C-myc Expression In Pediatric Anaplastic Large Cell Lymphomas. Am J Path 161 875-883, 2002

11. Raetz EA, Kim MKH, Moos PJ, Carlson M, Bruggers C, Hooper D, Foote L, Liu T, Seeger R and Carroll WL. Identification of genes that are transcriptionally regulated by Myc in childhood tumors (under review).

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Anne M. Hurlet, M.D., Associate Attending
1.
Mayer SA, Sacco R, Hurlet-Jensen A, Shi T, Mohr JP: Free protein S deficiency in acute ishemic stroke: a case control study.Stroke 24:224-227, 1993

2. Kugler S, Anderson B, Cross D, Sharif Z, Sano M, Haggerty R, Prohovnik I, Hurlet-Jensen A, Hilal S Mohr JP et al.: Abnormal cranial magnetic resonance imaging scans in sickle-cell disease. Neurological correlates and clinical implications. Archives of Neurology. 50:629-35, 1993

3. Hurlet-Jensen A, Prohovnik I, Pavlakis S G, Piomelli .: Effect of total hemoglobin and hemoglobin S on cerebral blood flow during transfusion therapy to prevent stroke in Sickle Cell Disease. Stroke. 25: 1688-1692,1994

4. Venketasubramanian N, Prohovnik I,Hurlet A, Mohr JP: Middle cerebral artery velocity changes during transfusion in sickle cell anemia. Stroke 25:2153-2158, 1994

5. Levin TL, Sheth SS, Hurlet A, Commerci SC, Ruzal-Shapiro C., Piomelli S, Berdon WE. MR marrow sign of iron overload in transfusion-dependant patients with sickle cell disease. Pediatric Radioloy 1995; 25:614-619

6. Comerci SCD, Levin T, Ruzal-Shapiro C, Berdon W, Beckwith JB, Hibshoosh H, Hurlet-Jensen A, Sitartz AL Benign pediatric adenomatous lesions of the kidney presenting with polycytemia: Imaging findings. Pediatric Radiology 1996;198:265-68

7. Sano M, Haggerty R, Kugler S, Martin B, Prohovnik, Hurlet-Jensen A, Piomelli S, DeVivo D Neuropsychological concequences of the Sickle Cell Disease. Neuropsychiatry, Neuropsychology and Behavioral Neurology 1996; 9:242-247

8. Levin TL, Berdon WE, Haller JO, Ruzal-Shapiro C, Hurlet-Jensen A. Intrasplenic masses of "preserved" splenic tissue in sickle cell disease: correlation of imaging findings (CT, ultrasound, MRI and nuclear scintigraphy. Pediatric Radiology 1996 26: 646-9

9. Koumbourlis A,C, Hurlet-Jensen A., Bye MR. Lung function in infants with sickle cell disease. Pediatric Pulmonology 1997, 24:277-281

10. Sheth S, Ruzal-Shapiro C., Hurlet-Jensen A., Piomelli S, Berdon WE. Pulmonary embolism developing in patients with sickle cell disease on hypertransfusion and IV desferioxamine chelation therapy. Pediatric Radiology 1997 27: 926-928

11. Adams R., Mckie V., Brambilla D, Carl E., Gallager D., Nichols F., Roach S, Abboud M., Berman B., Files B., Hsu L., Hurlet A. , Miller S., Olivieri N., Pegelow C., Vichinsky E., Wang W., Woods G.,, Wright E,Kultar A., Hanger S., Tighe F., Lewin J., Cure J., Zimmerman R., Waclawiw Stroke Prevention in Sickle Cell Disease. Sickle cell anemia. J Controlled Clin Trials 1998 19:110-29

12. Adams RJ, McKie VC, Hsu L, Files B, Vichinsky E, Pegelow C, Abboud M, Callagher D, Nichols FT, Bonds DR, Brambilla D, Goods G, Olivieri N, Driscoll C, Miller S, Wang W, Hurlet A, scher C, Carl E, Jones AM Roach S, Wright E, Zimmerman R, Waclawiw M. Prevention of a first stroke by transfusion in children with Sickle Cell Anemia and abnormal results on transcranial doppler ultrasonnography N Engl J Med 1998;339:5-11

13. Koumbourlis AC, Zar HJ, Hurlet-Jensen A, Goldberg MR. Prevalence and reversibility of lower airway obstruction in children with sickle cell disease. J Pediatr. 2001;138: 188-92

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W. Beau Mitchell, M.D., Instructor

1. B Mitchell, J Li, J Ruan, A Michelson, J Bussel, BS Coller, DL French. Glanzmann Thrombasthenia (GT) Mutations Within the Second and Third Calcium-Binding Regions of aIIb Affect Biogenesis of aIIbb3. Blood 2000 96(11):816a. Abstract and oral presentation, American Society of Hematology 42nd annual meeting, December 2000
.
2. B Mitchell, J Ruan, J Li, DL French. Two New Mutations Within the Second and Third Calcium-Binding Regions of aIIb Result in Glanzmann Thrombasthenia. Poster presentation at Mount Sinai School of Medicine Pediatric Research Day, Mount Sinai Medical Center, NY, May 25, 2000.

3. B Mitchell, J Li, HJ Weiss, BS Coller, DL French. A Glanzmann Thrombasthenia Mutation in aIIb Resulting in Deletion of the Transmembrane Domain Impairs aIIbb3 Complex Formation and Processing. Poster presentation at the18th Congress of the International Society on Thrombosis and Haemostasis, July 2001.

4. B Mitchell, S Usher, J Li, H Singh, L Isola, S Fruchtman, BS Coller, H Peretz, DL French. Megakaryocyte Engraftment Following Non-myeloablative Transplantation (NMT): Documentation Using IIb Polymorphisms. Poster presentation at the American Society of Hematology 43rd annual meeting, December 2001.

5. S Nair, J Li, B Mitchell, D Mohanty, BS Coller, DL French. Two new b3 integrin mutations I Indian patients with Glanzmann thrombasthenia: localization of mutations affecting cysteine residues in integrin b3 Thrombosis and Hemostasis, in press

6. Submitted to Blood: WB Mitchell, J Li, F Singh, J Ruan, AD Michelson, J Bussel, BS Coller, DL French. Two Novel Mutations in the aIIb Calcium-Binding Domains Identify Hydrophobic Regions Essential for aIIbb3 Biogenesis

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